Former Champions Asante Kotoko will host the newly promoted side, Heart of Lions at the Kumasi Baba Yara Sports Stadium.
Dr Nartey Ogum has paraded a strong starting XI to face Kpando Hearts of Lions this evening at the Baba Yara Stadium.
Lions last played in the Ghana Premier League in 2015 where they were relegated after finishing 14th place in the 16 club league.
Asante Kotoko has won one in the last two encounters between the two sides.
Heart of Lions have also recorded one victory over the Kotoko in their last two games- (Heart of Lions 3-1 Asante Kotoko, Asante Kotoko 4-0 Heart of Lions).
Asante Kotoko have appointed their former head coach Dr. Prosper Nartey Ogum with the signing of Yussif Nurudeen Mohammed, Sampson Asamoah, Nanabayin Amoah, Baba Yahaya, Kalo Ouattara and Henry Ansu.
Asante Kotoko lineup
Heart of Lions were promoted to the Premier League after finishing top in Zone Three of the Access Bank division one league and have maintained their head coach, Salifu Fatawu with players like Dickson Sakabutu, Thomas Kwabena Osae, new signing, Seedorf Asante, Denis Hutor and Ruben Hennesy all available for their first game.
The game will kick off at 6pm and will be live on StarTimes.